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‘Extremely promising’: 1st dose of COVID vaccine cuts illness

Data from two separate research revealed within the UK, one in England and one other in Scotland, have proven vaccines in opposition to COVID-19 are efficient in chopping illness transmission and hospitalisations ranging from the primary dose.

Analysis from Public Health England (PHE) revealed on Monday reveals that the vaccine manufactured by Pfizer-BioNTech reduces the chance of catching an infection by greater than 70 p.c after the primary dose. That danger is lowered by 85 p.c after a second dose.

“Overall, we’re seeing a really strong effect to reducing any infection, asymptomatic and symptomatic,” PHE’s strategic response director Susan Hopkins informed a media briefing.

In a press release posted on social media, Matt Hancock, the secretary of state for Health & Social Care, welcomed the event as “incredibly good news”.

“It shows that the vaccines work and it shows that vaccines save lives.”

The public well being physique’s research of real-world information additionally reveals these vaccinated individuals who do turn out to be contaminated are far much less prone to die or be hospitalised.

Hospitalisation and dying from the virus is lowered by greater than 75 p.c in those that have acquired a dose of the Pfizer-BioNTech vaccine, in response to the evaluation.


The UK is among the many world’s hardest-hit international locations by the COVID-19 pandemic, with nearly 121,000 deaths, in response to information from Johns Hopkins University.

It was the primary nation to start mass vaccinations in December and greater than 17 million folks – roughly one-third of the UK’s grownup inhabitants – have now acquired not less than their first dose of the vaccine.

“We will see much more data over the coming weeks and months but we should be very encouraged by these initial findings,” Dr Mary Ramsay, Head of Immunisation at Public Health England, stated.

‘National evidence’

At the identical time, a research in Scotland has proven the Pfizer-BioNTech and Oxford-AstraZeneca vaccinations have led to a discount in COVID-19 admissions to hospitals after the primary dose.

The research, led by the University of Edinburgh, discovered that by the fourth week after receiving the preliminary dose the Pfizer vaccine lowered the chance of hospitalisation from COVID-19 by as much as 85 p.c.

A separate research in Scotland has proven that the Oxford-AstraZeneca vaccine lowered the chance of hospitalisation by 94 p.c [File: Luca Zennaro/EPA]

The Oxford-AstraZeneca vaccine lowered the chance by 94 p.c.

“These results are very encouraging and have given us great reasons to be optimistic for the future,” Dr Aziz Sheikh, who led the analysis, stated in a press release.

“We now have nationwide proof – throughout a complete nation – that vaccination supplies safety in opposition to COVID-19 hospitalisations.

“Roll out of the first vaccine dose now needs to be accelerated globally to help overcome this terrible disease,” he added.

The analysis in contrast the outcomes of those that had acquired their first jab with those that had not.

It discovered that vaccination was related to an 81-percent discount in hospitalisation danger within the fourth week amongst these aged 80 years and over, when the outcomes for each vaccines had been mixed.

‘Extremely promising’

The mission, which used affected person information to trace the pandemic and the vaccine roll out in real-time, analysed a dataset overlaying the complete Scottish inhabitants of 5.4 million between December 8 and February 15.

Some 1.14 million vaccines had been administered to 21 p.c of the Scottish inhabitants throughout the interval.

Some 650,000 folks got the Pfizer vaccine whereas 490,000 had the Oxford-AstraZeneca vaccine.

It is the primary analysis to explain the impact of the vaccinations on stopping extreme illness leading to hospitalisation throughout a complete nation.

Previous outcomes about vaccine efficacy have come from medical trials.

The research staff stated the findings had been relevant to different international locations utilizing the Pfizer and Oxford-AstraZeneca vaccines.

The information reported “is extremely promising,” stated Arne Akbar, the president of the British Society for Immunology.

“Although there does seem to be some difference in effectiveness levels measured across age groups, the reduction in hospitalisations for the older age groups is still impressively high,” he stated.

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Updated on February 28, 2021 9:04 pm

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