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Why Blood Type May Matter for COVID Infection

WEDNESDAY, March 3, 2021 (HealthDay News) — A brand new examine offers additional proof that individuals with sure blood varieties could also be extra prone to contract COVID-19.

Specifically, it discovered that the brand new coronavirus (SARS-CoV-2) is especially drawn to the blood group A antigen discovered on respiratory cells.

The researchers centered on a protein on the floor of the SARS-CoV-2 virus referred to as the receptor binding area (RBD), which is the a part of the virus that attaches to the host cells. That makes it an necessary goal for scientists making an attempt to find out how the virus infects folks.

In this laboratory examine, the crew assessed how the SARS-CoV-2 RBD interacted with respiratory and crimson blood cells in A, B and O blood varieties.

The outcomes confirmed that the SARS-CoV-2 RBD had a robust choice for binding to blood group A discovered on respiratory cells, however had no choice for blood group A crimson blood cells, or different blood teams discovered on respiratory or crimson cells.

The SARS-CoV-2 RBD’s choice to acknowledge and fasten to the blood sort A antigen discovered within the lungs of individuals with blood sort A might present perception into the potential hyperlink between blood group A and COVID-19 an infection, in line with the authors of the examine. It was printed March 3 within the journal Blood Advances.

“It is interesting that the viral RBD only really prefers the type of blood group A antigens that are on respiratory cells, which are presumably how the virus is entering most patients and infecting them,” stated examine creator Dr. Sean Stowell, from Brigham and Women’s Hospital in Boston.

“Blood type is a challenge because it is inherited and not something we can change,” Stowell stated in a journal news launch. “But if we can better understand how the virus interacts with blood groups in people, we may be able to find new medicines or methods of prevention.”

These findings alone cannot totally describe or predict how coronaviruses would have an effect on sufferers of varied blood varieties, the researchers famous.

“Our observation is not the only mechanism responsible for what we are seeing clinically, but it could explain some of the influence of blood type on COVID-19 infection,” Stowell and his crew stated.

More info

The U.S. Centers for Disease Control and Prevention has extra on COVID-19.

SOURCE: Blood Advances, news launch, March 3, 2021

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