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Thursday, September 16, 2021

Older age, chronic co-morbidities associated with more severe COVID disease in children

Over the course of the pandemic, researchers nationwide seen variations in COVID-19 disease between children and adults.

While danger components for hospitalization and poor outcomes are effectively documented in adults, much less is understood in regards to the medical components associated with COVID disease severity in children.

In an effort to help mitigation methods for children who’re at excessive danger of growing severe COVID disease, a bunch of physicians at Monroe Carell Jr. Children’s Hospital at Vanderbilt studied knowledge from 45 children’s hospitals across the nation — 20,000 sufferers had been included.

“This is one of the largest multicenter studies of children with COVID-19 in the United States,” mentioned James Antoon, MD, PhD, FAAP, assistant professor of Pediatrics at Children’s Hospital and lead creator of the research.

“And given the recent, concerning increases in COVID cases nationwide and the fact that the vast majority of children remain unvaccinated and susceptible, these findings should be taken into account when considering preventive strategies in schools and planning vaccinations when available for children less than 12 years of age,” he mentioned.

The research, “Factors Associated with COVID-19 Disease Severity in U.S. Children,” revealed in the Journal of Hospital Medicine, decided the components associated with severe disease and poor well being outcomes amongst children presenting to the hospital with COVID. These included older age and chronic co-morbidities akin to weight problems, diabetes and neurologic circumstances, amongst others.

“These factors help identify vulnerable children who are most likely to require hospitalization or develop severe COVID-19 disease,” mentioned Antoon. “Our findings also highlight children who should be prioritized for COVID-19 vaccines when approved by the FDA.”

The retrospective cohort research famous that roughly 1 out of each 4 children admitted to the hospital with COVID developed severe disease and required ICU care throughout April and September, 2020.

“Across the country there is a raging debate on how best to protect children and schools from COVID-19,” mentioned Antoon. “Some children are at elevated danger for more severe disease and plenty of of them usually are not but eligible for vaccination towards COVID.

“With schools opening and some already in session, these children need to be protected by vaccinating as many people as possible while also using practical strategies to limit spread, such as masking, distancing and ventilation.”

Study investigators hope that the findings will buoy mitigation efforts that proved most helpful for children and adolescents in the course of the pandemic, together with distant studying, social distancing, hand-washing and mask-wearing each for college students and academics.

Story Source:

Materials supplied by Vanderbilt University Medical Center. Original written by Jessica Pasley. Note: Content could also be edited for type and size.

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