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Having a Cousin or Grandparent With Colon Cancer Raises Your Risk

By Steven ReinbergHealthDay Reporter

WEDNESDAY, Sept. 15, 2021 (HealthDay News) — Colon most cancers threat runs in households, and it isn’t simply a mum or dad or sibling having had the illness that ought to concern you.

If you’ve got a second- or third-degree relative who had colon most cancers at an early age, your odds of getting the illness considerably enhance, a new examine finds.

First-degree family embrace dad and mom, youngsters and siblings. Second-degree family embrace aunts, uncles, grandparents, grandchildren, nieces and nephews. Third-degree family embrace first cousins, great-grandparents and great-grandchildren.

“Our study provides new insight into the magnitude of risk for more distant relatives of colorectal cancer cases, and in particular, for relatives of cases who were diagnosed before age 50,” mentioned researcher Heather Ochs-Balcom, an affiliate professor of epidemiology and environmental well being with the University at Buffalo (N.Y.) School of Public Health and Health Professions.

“This work is important given the rising rates of early-onset colorectal cancer,” she mentioned in a college news launch. The researchers, from the University at Buffalo and the University of Utah, referred to early-onset colon most cancers as circumstances recognized earlier than age 50.

First-degree family of somebody recognized with early-onset colon most cancers are six occasions extra prone to develop colon most cancers earlier than age 50; second-degree family are thrice extra doubtless, and third-degree family are about 1.5 occasions extra doubtless, investigators discovered.

For the examine, they reviewed greater than 1,500 early-onset colon most cancers circumstances within the Utah Cancer Registry.

Researchers additionally discovered that individuals have a 2.6-fold larger threat of colon most cancers at any age if they’ve a first-degree relative with early-onset colon most cancers. And the chance is about two occasions larger for second-degree family, and 1.3 occasions larger for third-degree family.

These findings recommend that a colonoscopy screening earlier than age 50 could also be helpful for second-degree family and probably third-degree family of somebody who developed colon most cancers, not simply quick members of the family.

The report was revealed in August within the journal Cancer Epidemiology.

More info

For extra on colon most cancers, see the American Cancer Society.

SOURCE: University at Buffalo, news launch, Sept. 13, 2021

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